Mouse Microsatellite (STRP) Studies

Whole Genome Linkage Scan
&
Congenic / Consomic Line Construction

Resources
A total of 54 inbred strains have been typed for ~300 markers. CIDR provides several resources to assist investigators in their study design.

• Marker Set
• List of 54 strains genotyped at CIDR
• Interactive Queries
  
  • Informative Markers for a Cross
  • Panel Generator
  • Informative Markers for Multiple Strains
  • Informative Markers for Speed Congenics
• Complete data files of all allele call data for all markers and strains in different formats

Genome Scans
CIDR performs genotyping for mapping studies with inbred strains of mice by carrying out a 20 cM genome-wide scan. CIDR utilizes automated fluorescent microsatellite analysis with informative markers for the specified cross. Only mouse mapping projects with at least 80 animals will be accepted.

Speed Congenic / Consomic Line Construction
CIDR performs genotyping on samples from backcross generations N2 and N3 for investigators who want to use a marker-assisted breeding strategy to accelerate the production of congenic and consomic strains of mice, so-called "speed congenics and consomics." Each set of samples will be genotyped with a set of ~80-100 microsatellite markers spaced approximately every 20 cM across the mouse genome. The N3 generation will be typed with a set of markers interspersed between those used in the N2 generation. For each generation, the investigator should submit a minimum of 80 animals.

Statistical Genetics Consultation
Statistical genetics services are not available for mouse projects.

Pricing
Genotyping charges are based on the source of support for the research project and the type of service. Services are FREE to extramural investigators for projects supported by one of the twelve participating institutes since CIDR is funded through a chargeback mechanism from those institutes. For additional information on pricing, and for pricing details for non-extramural grantees, click here.

Application Process
CIDR services are available to all investigators through competitive peer review. Applications are evaluated by the CIDR Access Committee (CAC) for scientific merit. The application and thee CAC's recommendations are reviewed by the Board of Governors (BOG). The BOG determines which projects are granted access to CIDR. All projects require prior approval from the institute liaison before an application is submitted to CIDR.

Genome Scans	Congenic / Consomic Line Construction
General Application & Access Information	General Application & Access Information
Application Deadlines	Application Deadlines
Application	Application